Week 2 MLB Fantasy Baseball Preview: Must-Start Pitchers, Hitter Matchups & Weather Watch (March 31-April 6)

Complete Week 2 fantasy baseball breakdown featuring top two-start pitchers, optimal hitter matchups, weather concerns, and key scheduling insights for March 31-April 6.

MLB Fantasy Baseball Week 2: Complete Guide

The first full week of the 2025 MLB season brings critical decisions for fantasy managers as teams settle into their rotations. With most clubs playing 6-7 games, understanding the nuances of Week 2 matchups could give you an early edge in your league.

Key Week 2 Considerations:

  • Two-start pitchers dominate rotation schedules (mostly back-of-rotation arms)
  • Early-season weather concerns in northern ballparks
  • Cincinnati Reds and Philadelphia Phillies lead with 7-game weeks
  • First look at Sutter Health Park (Athletics' new home in Sacramento)

The full Week 2 schedule runs from Monday, March 31 through Sunday, April 6 with all 30 teams in action.

Starting Pitcher Analysis

Top 10 Two-Start Pitchers:

Rank Pitcher Team 1st Start 2nd Start Projection
1 Tyler Glasnow LAD vs. ATL @PHI 24-25 pts
2 Corbin Burnes ARI @NYY @WSH 23-24 pts
3 Cristopher Sánchez PHI vs. COL vs. LAD 22-23 pts
4 Bowden Francis TOR vs. WSH @NYM 21-22 pts
5 Ronel Blanco HOU vs. SF @MIN 20-21 pts

Notable Omissions:

  • Zack Wheeler (PHI) only gets one start (vs. COL)
  • Early-season workload management affects top aces

Weather Watch:

Northern cities like New York, Boston, and Chicago face potential rain/snow delays. Monitor:

  • Yankees-Rays (Bronx, 48° forecast)
  • Red Sox-Orioles (Boston, 45° with rain)
  • Cubs-Athletics (Sacramento, 52° but dry)

Hitter Matchup Ratings

Top 5 Teams for Hitters:

  1. Cincinnati Reds (7 games - 4 @MIL, 3 vs. TEX)

    • Elite: 10/10 overall rating on Friday vs. MIL
    • Play 3 games at hitter-friendly Great American Ball Park
  2. Detroit Tigers (6 games - 3 @SEA, 3 vs. CWS)

    • Face Mariners in cold Seattle weather, then weak White Sox rotation
  3. Philadelphia Phillies (7 home games)

    • Benefit from facing COL pitching staff at Citizens Bank Park

Park Factors to Watch:

  • Sutter Health Park (OAK): Initial data suggests pitcher-friendly dimensions with extra-base hit potential
  • Coors Field (COL): Always boosts offensive numbers, especially early in season
  • Great American Ball Park (CIN): Historically one of MLB's most hitter-friendly venues

Daily Fantasy Strategy

Best Stacking Opportunities:

  • Monday 3/31: Reds (vs. TEX) - Facing Kumar Rocker in debut
  • Wednesday 4/2: Phillies (vs. COL) - vs. Kyle Freeland at home
  • Saturday 4/5: Dodgers (@PHI) - Against softer part of Phillies rotation

Sleeper Picks:

  • OF James Outman (LAD): Hot spring, gets 2 games at hitter-friendly Philly
  • 2B Bryson Stott (PHI): 7 home games against weak COL/LAD pitching
  • SP Garrett Crochet (CWS): Increased velocity, gets BAL in cold Chicago

Final Thoughts

Week 2 presents unique challenges with unpredictable weather and rotations still settling. Focus on:

  1. Two-start pitchers with favorable matchups
  2. Hitters in warm-weather venues or hitter-friendly parks
  3. Teams playing 7 games (CIN, PHI)
  4. Early-season bullpen usage trends

Remember: These are early-season projections. Be ready to adjust as real-game data emerges.

What to Read Next

Unlock Late-Season MLB Fantasy Success: Top Players to Target Before the Trade Deadline
MLB

Unlock Late-Season MLB Fantasy Success: Top Players to Target Before the Trade Deadline

Discover the top MLB players to target before the fantasy baseball trade deadline to boost your team's performance in the final stretch of the 2025 season.

New York Baseball in Crisis: Can the Yankees and Mets Salvage Their Seasons?
MLB

New York Baseball in Crisis: Can the Yankees and Mets Salvage Their Seasons?

The New York Yankees and Mets face mounting challenges as their playoff hopes hang in the balance. Can they turn things around before October?

White Sox Boost Roster with Vargas and Gómez Ahead of Crucial Series
MLB

White Sox Boost Roster with Vargas and Gómez Ahead of Crucial Series

The Chicago White Sox have activated Miguel Vargas from the injured list and promoted Yoendrys Gómez to strengthen their lineup against Detroit.

Ultimate MLB Fantasy Baseball Lineup and Betting Guide for Wednesday
MLB

Ultimate MLB Fantasy Baseball Lineup and Betting Guide for Wednesday

Get expert advice on setting your MLB fantasy baseball lineup and placing bets for Wednesday's games. Includes pitcher rankings, hitter insights, and betting tips.

MLB Bullpen Breakdown: Key Closers to Watch in the 2025 Stretch Run
MLB

MLB Bullpen Breakdown: Key Closers to Watch in the 2025 Stretch Run

Explore the top MLB bullpen strategies and closers to watch as the 2025 season heads into its crucial final stretch. Key insights on David Bednar, Kyle Finnegan, and more.

MLB 2025 Season: Revisiting the Top 50 Player Rankings and Surprising Midseason Shifts
MLB

MLB 2025 Season: Revisiting the Top 50 Player Rankings and Surprising Midseason Shifts

Explore the latest MLB 2025 midseason player rankings, expert critiques, and surprising shifts in the top 50 list. Discover who's rising, who's falling, and what's next.

MLB 2025 Season: Top 50 Players Power Rankings and Performance Insights
MLB

MLB 2025 Season: Top 50 Players Power Rankings and Performance Insights

Explore the updated top 50 MLB player rankings for the 2025 season, featuring insights on standout performances and future expectations.

Byron Buxton Returns to Boost Twins as They Face Yankees in Crucial Series
MLB

Byron Buxton Returns to Boost Twins as They Face Yankees in Crucial Series

All-Star Byron Buxton rejoins the Minnesota Twins after recovering from injury, ready to make an impact in the series against the New York Yankees.

Gerrit Cole's Road to Recovery: Yankees Ace Takes Major Step Post-Tommy John Surgery
MLB

Gerrit Cole's Road to Recovery: Yankees Ace Takes Major Step Post-Tommy John Surgery

Yankees' star pitcher Gerrit Cole makes significant progress in his recovery from Tommy John surgery with 20 successful throws off flat ground.

Ultimate MLB Fantasy Baseball and Betting Guide for Tuesday: Expert Tips and Lineup Strategies
MLB

Ultimate MLB Fantasy Baseball and Betting Guide for Tuesday: Expert Tips and Lineup Strategies

Get expert advice on setting your fantasy baseball lineup and placing MLB bets for Tuesday's games. Includes starting pitcher rankings, betting tips, and more.

Top MLB Fantasy Pickups: Keaschall and Rising Stars to Watch Post-Trade Deadline
MLB

Top MLB Fantasy Pickups: Keaschall and Rising Stars to Watch Post-Trade Deadline

Discover the top MLB fantasy pickups post-trade deadline, featuring Luke Keaschall and other rising stars to boost your team.

Ultimate MLB Fantasy Baseball Guide: Expert Lineup Advice & Betting Tips for Monday's Games
MLB

Ultimate MLB Fantasy Baseball Guide: Expert Lineup Advice & Betting Tips for Monday's Games

Get expert MLB fantasy baseball lineup advice and betting tips for Monday's games. Optimize your picks with ESPN Fantasy insights and strategies.

MLB Playoff Race 2025: Contenders, Long Shots, and Teams with Work to Do
MLB

MLB Playoff Race 2025: Contenders, Long Shots, and Teams with Work to Do

A comprehensive breakdown of the 2025 MLB playoff race, highlighting the top contenders, teams with work to do, and the long shots aiming for October baseball.

Aaron Boone Ejected Again: Yankees Manager's Fiery Season Continues
MLB

Aaron Boone Ejected Again: Yankees Manager's Fiery Season Continues

Yankees manager Aaron Boone faces his fifth ejection this season, highlighting a fiery streak in MLB.

Manny Machado's Hidden Ball Trick Backfires: A Costly Play in Padres vs. Red Sox Clash
MLB

Manny Machado's Hidden Ball Trick Backfires: A Costly Play in Padres vs. Red Sox Clash

Manny Machado's attempted hidden ball trick against the Red Sox led to a balk, costing the Padres a crucial run in a tense MLB game.

Load More

We use essential cookies to make our site work. With your consent, we may also use non-essential cookies to improve user experience and analyze website traffic. By clicking "Accept," you agree to our website's cookie use as described in our Cookie Policy.